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J Clin Psychiatry. 2001 Nov;62(11):841-2.

Dopamine system stabilizers, aripiprazole, and the next generation of antipsychotics, part 1, "Goldilocks" actions at dopamine receptors.

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  • 1Neuroscience Education Institute in Carlsbad, Calif 92009, USA.

Abstract

Dopamine system stabilizers are a potential new class of antipsychotic agents without motor side effects. All known effective antipsychotics act at D2 receptors. A novel concept for an antipsychotic without motor side effects is to stabilize these receptors rather than block them harshly.

PMID:
11775041
[PubMed - indexed for MEDLINE]
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