Arch Pediatr. 2001 Nov;8(11):1218-21.

[Aerosolized iloprost therapy in an infant with chronic pulmonary hypertension after a neonatal arterial switch operation].

[Article in French]

Source

Centre chirurgical Marie-Lannelongue, 133, avenue de la Résistance, 92350 Le-Plessis-Robinson, France. vlambert@ccml.com

Abstract

The treatment of chronic pulmonary hypertension with prostacyclin in children is prone to severe complications due to mandatory long-term venous therapy. Inhaled iloprost has been evaluated in adult patients with good preliminary results. CASE REPORT: We report our experience of the use of aerosolized iloprost in an infant treated for pulmonary hypertension associated to a right ventricular failure, which occurred after a neonatal arterial switch operation for transposition of the great arteries. For nine months, hemodynamic and functional status improved and the quality of life was satisfactory at home. CONCLUSION: If further experiences and studies support this observation, aerosolized iloprost could be an alternative to prostacyclin venous therapy in treating children with chronic pulmonary hypertension.

PMID:: 11760674; [PubMed - indexed for MEDLINE]

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