Scand J Infect Dis. 2001;33(10):788-9.

Clinical ergotism induced by ritonavir.

Vila A, Mykietiuk A, Bonvehì P, Temporiti E, Urueña A, Herrera F.

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Department of Internal Medicine, CEMIC, Norberto Quirno, Buenos Aires, Argentina.

Abstract

Ritonavir strongly inhibits cytochrome P450, thus altering the metabolism of other drugs. We report on an HIV-positive man who, on his 13th day of ritonavir therapy, developed severe ergotism after self-administration of low doses of ergotamine. Drug interactions, the degree of responsibility of the patient and the availability of over-the-counter medications must be considered when prescribing antiretroviral therapy.

PMID:: 11728055; [PubMed - indexed for MEDLINE]

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Cited by 1 PubMed Central article

Holy fire in an HIV-positive man: a case of 21st-century ergotism. [CMAJ. 2010]
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