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Cancer Immunol Immunother. 2001 Oct;50(8):391-6.

Fever and cancer in perspective.

Author information

  • F. Hoffmann-La Roche Ltd., Pharma Research, Basel, Switzerland. uwe.hobohm@roche.com

Abstract

CONTEXT:

A relationship between feverish infection and concurrent remission from cancer has been known about for a very long time. However, a systematic investigation of the phenomenon has not yet been made.

OBJECTIVE:

To bring together the isolated observations about the coincidence of spontaneous remissions with feverish infections and William Coley's seminal work, as a basis for devising an immunological hypothesis about the putative anti-cancer effect of fever.

CONCLUSION:

Fever induction under medical guidance may be considered as part of a therapy regimen for cancers of mesodermal origin.

PMID:
11726133
[PubMed - indexed for MEDLINE]
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