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Radiology. 2001 Dec;221(3):641-9.

Clinical utility of bilateral whole-breast US in the evaluation of women with dense breast tissue.

Author information

  • Strax Institute, 4300 N University Dr, Suite E-200, Lauderhill, FL 33351, USA. skaplan659@aol.com

Abstract

PURPOSE:

To evaluate the clinical utility of bilateral whole-breast ultrasonography (US) as an adjunct examination to mammography in asymptomatic women with dense (Breast Imaging Reporting and Data System [BI-RADS] density category 3 or 4) breast tissue.

MATERIALS AND METHODS:

Between July 1998 and April 2000, 1,862 patients with negative findings at clinical examinations, negative mammographic results, and breast tissue with BI-RADS category 3 or 4 density were evaluated with bilateral whole-breast US for occult cystic and solid masses, areas of architectural distortion, and acoustic shadowing. Suggestive findings were compared with tissue diagnoses from US-guided core biopsy specimens. US was initially performed by a US or a mammography technologist. The average time to perform the examination was approximately 10 minutes. Abnormal findings were corroborated by a fellowship-trained breast-imaging radiologist.

RESULTS:

In the 1,862 women examined with bilateral whole-breast US, 57 biopsies were recommended in 56 patients; follow-up data were available in 51 of the 56 patients. Six breast cancers were detected (cancer detection rate, 0.3%).

CONCLUSION:

Bilateral whole-breast US, when performed in patients with dense (BI-RADS category 3 or 4 density) breast tissue, is useful in detecting breast cancer not discovered with mammography or clinical breast examination. The 0.3% cancer detection rate compares favorably with that of screening mammography and with that in previously published studies involving bilateral whole-breast US.

Comment in

  • Screening breast US. [Radiology. 2003]
  • Screening breast US. [Radiology. 2002]
PMID:
11719658
[PubMed - indexed for MEDLINE]
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