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    Cell. 2001 Nov 16;107(4):419-25.

    Reconstructing/deconstructing the earliest eukaryotes: how comparative genomics can help.

    Dacks JB, Doolittle WF.

    Program in Evolutionary Biology, Canadian Institute for Advanced Research, Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.

    Abstract

    We could reconstruct the evolution of eukaryote-specific molecular and cellular machinery if some living eukaryotes retained primitive cellular structures and we knew which eukaryotes these were. It's not clear that either is the case, but the expanding protist genomic database could help us in several ways.

    PMID: 11719183 [PubMed - indexed for MEDLINE]

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