Format

Send to

Choose Destination
See comment in PubMed Commons below
Trends Cell Biol. 2001 Dec;11(12):492-6.

Shrinking patches and slippery rafts: scales of domains in the plasma membrane.

Author information

  • 1Biology Dept, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA. edidin@jhu.edu

Abstract

Many types of experiment show that the plasma membranes of cells are patchy and locally differentiated into domains. Some of these domains seem to arise through the confinement of diffusible membrane proteins. Others might arise through lipid-lipid interactions. Both types of domain are transient on a biological timescale but both could create local conditions that enhance molecular interactions, such as those that occur in receptor-mediated signaling.

PMID:
11719055
[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk