[Granulomatous slack skin: partial remission following intralesional administration of interferon-alpha and PUVA]

Hautarzt. 2001 Oct;52(10 Pt 2):985-8. doi: 10.1007/s001050170014.
[Article in German]

Abstract

Granulomatous slack skin (GSS) is a rare cutaneous T-cell lymphoma which typically runs a protracted and indolent course. On histopathological assessment lymphoid infiltrates with multinucleated giant cells in the dermis and subcutis with elastophagocytosis can be observed. Skin lesions are characterized by pendulous folds. We report on the successful response of the lesions to intralesional interferon alpha combined with PUVA.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antineoplastic Agents / administration & dosage*
  • Follow-Up Studies
  • Humans
  • Injections, Intralesional
  • Interferon-alpha / administration & dosage*
  • Lymphoma, T-Cell, Cutaneous / diagnosis
  • Lymphoma, T-Cell, Cutaneous / drug therapy*
  • Lymphoma, T-Cell, Cutaneous / pathology
  • Male
  • PUVA Therapy*
  • Remission Induction
  • Skin / pathology
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology
  • Time Factors

Substances

  • Antineoplastic Agents
  • Interferon-alpha