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Curr Psychiatry Rep. 2001 Dec;3(6):451-62.

Rapid cycling bipolar disease: new concepts and treatments.

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  • Department of Psychiatry, University of Colorado School of Medicine, 4200 East 9th Avenue, Denver, CO 80262, USA. Steven.Dubovsky@UCHSC.edu


Having been recognized by Kraeplin at the beginning of the 20th century, rapid cycling was first described as a specific entity by Dunner et al. in 1974. The prevalence of rapid cycling ranges from 12% to 20% in patients with bipolar disorder who are not selected for a high rate of cycling.

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