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Cochrane Database Syst Rev. 2001;(4):CD002162.

Oral steroids for bronchiectasis (stable and acute exacerbations).

Author information

  • 1Public Health Sciences, St George's Hospital Medical School, Cranmer Terrace, Tooting, London, UK, SW17 0RE. tlassers@sghms.ac.uk

Abstract

BACKGROUND:

Inflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasis

OBJECTIVES:

To determine the efficacy of oral corticosteroids in acute and stable bronchiectasis

SEARCH STRATEGY:

The Cochrane Airways Group clinical trials register, derived from MEDLINE, EMBASE and hand searching of major journals, was searched using the terms bronchiectasis AND corticosteroid* OR (beclomethasone, cortisone, deflazacort, hydrocortisone, methylprednisolone, prednisolone, dexamethasone and triamcinolone

SELECTION CRITERIA:

Only randomised controlled trials were considered

DATA COLLECTION AND ANALYSIS:

No trials met the inclusion criteria for the review

MAIN RESULTS:

No randomised controlled trials were identified

REVIEWER'S CONCLUSIONS:

There are no randomised trials upon which to make recommendations about the use of oral corticosteroids in acute or stable bronchiectasis.

PMID:
11687146
[PubMed - indexed for MEDLINE]
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