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J Rheumatol. 2001 Oct;28(10):2310-4.

Number of births, interpregnancy interval, and subsequent pregnancy rate after a diagnosis of inflammatory rheumatic disease in Norwegian women.

Author information

  • 1Department of Rheumatology, Center for Mothers with Rheumatic Disease, University Hospital of Trondheim, Norway. johan.skomsvoll@medisin.ntnu.no



To study female reproduction, i.e., number of births, subsequent pregnancy rate, and interpregnancy interval after diagnosis of inflammatory rheumatic disease.


In a national population based cohort study, reproduction in mothers with rheumatic disease, registered with the Medical Birth Registry of Norway 1967-1995, were compared to mothers without such diagnoses.


After diagnosis, women with rheumatic disease had a statistically significant lower mean number of births, a shorter time span of reproduction, longer interpregnancy intervals, and a reduced subsequent pregnancy rate.


Altered reproduction observed in women with a rheumatic disease might reflect various mechanisms not accounted for in this study, but possibly related to the disease process, functional impairment, or medical treatment.

[PubMed - indexed for MEDLINE]
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