Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genome Biol. 2001;2(10):REVIEWS2002. Epub 2001 Sep 27.

Having a BLAST with bioinformatics (and avoiding BLASTphemy).

Author information

  • 1Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390-8591, USA. Alexander.Pertsemlidis@UTSouthwestern.edu

Abstract

Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.

PMID:
11597340
[PubMed - indexed for MEDLINE]
PMCID:
PMC138974
Free PMC Article

Images from this publication.See all images (6)Free text

Box 1
Figure 1
Figure 2
Figure 3
Box 2
Figure 4
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk