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1: Genome Biol. 2001;2(10):REVIEWS1028. Epub 2001 Sep 14.Click here to read Click here to read Links

Functional genomics and metal metabolism.

Eide DJ.

Department of Nutritional Sciences, University of Missouri-Columbia, Columbia, MO 65211, USA. eided@missouri.edu

Metal ions are essential nutrients, yet they can also be toxic if they over-accumulate. Homeostatic mechanisms and detoxification systems therefore precisely control their intracellular levels and distribution. The tools of functional genomics are rapidly accelerating understanding in this field, particularly in the yeast Saccharomyces cerevisiae.

PMID: 11597338 [PubMed - indexed for MEDLINE]

PMCID: PMC138972