[Effect of total saponins of Panax notoginseng (TSPNS) on myocardial intracellular Ca2+ and activity of calcium pump of membrane of sarcoplasmic reticulum in SHR]

P Feng; H Jiang

[Effect of total saponins of Panax notoginseng (TSPNS) on myocardial intracellular Ca2+ and activity of calcium pump of membrane of sarcoplasmic reticulum in SHR]

Zhongguo Zhong Yao Za Zhi. 1998 Mar;23(3):173-5, inside backcover.

[Article in Chinese]

Authors

P Feng¹, H Jiang

Affiliation

¹ Zhejiang Traditional Chinese Medical College, Affiliated Hospital, Hangzhou 310006.

PMID: 11596240

Abstract

A comparative study was conducted on the action of TSPNS, NS and Captopril in treating SHR, with WKY of similar ages taken as normal control. The results demonstrate that TSPNS helps increase the effect of calcium pump on the membrane of sarcoplasmic reticulum, decrease the myocardial intracellular Ca2+ and reduce the mass of the left ventricular muscle.

MeSH terms

Animals
Calcium / metabolism*
Calcium-Transporting ATPases / metabolism*
Cell Membrane / metabolism
Myocardium / cytology
Myocardium / metabolism*
Panax / chemistry*
Plants, Medicinal*
Random Allocation
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Saponins / isolation & purification
Saponins / pharmacology*
Sarcoplasmic Reticulum / metabolism

Substances

Saponins
Calcium-Transporting ATPases
Calcium