Arch Neurol. 2001 Oct;58(10):1682-4.

Treatment of ballism and pseudobulbar affect with sertraline.

Source

Department of Neurology, Emory University, Atlanta, Ga, USA.

Abstract

BACKGROUND:

The pathogenesis of ballism is uncertain and may involve more than one mechanism; treatment is not always efficacious.

OBJECTIVE:

To provide evidence of a nondopaminergic mechanism and the potential for a prompt and nearly complete response to a serotonergic agent.

METHODS:

Report of 2 separate trials of sertraline hydrochloride in a single patient.

RESULTS:

Complete remission of symptoms within 48 hours of each drug trial.

CONCLUSION:

Sertraline may offer an alternative with a better adverse effect profile than dopamine receptor blockers in the treatment of patients with ballism.

PMID:: 11594930; [PubMed - indexed for MEDLINE]

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Treatment of ballism and pseudobulbar affect with sertraline.

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