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J Postgrad Med. 2001 Jan-Mar;47(1):55-61.

Neurobiological correlates of panic disorder and agoraphobia.

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  • 1Department of Psychiatry, Salmaniya Hospital, Bahrain.


Panic Disorder and agoraphobia offer considerable diagnostic and management challenges, particularly in general practice. We describe a typical case of panic disorder in a young adult. The recent advances in our understanding of brain functions can be used to explain to a certain extent the biologic basis of panic disorder. A hypothetical model integrating current views on panic disorder and agoraphobia has been proposed. The management principles including the role of cognitive therapy and pharmacotherapy have been discussed.

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