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An Med Interna. 2001 Aug;18(8):426-8.

[Cowden syndrome: clinical case presentation with oral lesions].

[Article in Spanish]

Author information

  • 1Servicio de Estomatología, Hospital General Universitario de Valencia, Avda. Blasco Ibáñez, 17, 46014 Valencia.

Abstract

Cowden syndrome is an autosomal-dominant inheritance disease, characterized by the presence of skin and oral mucosa multiple hamartomas and nodules, together with thyroid and breast anomalies and polyposis of the gastrointestinal tract, which tend to undergo malignant transformation, especially in breast and thyroids. Therefore, the oral lesions early diagnosis facilitates the identification of asintomatic lesions, in other parts of the body. This is the case in the report we are to present, in which the patient, probably with the Cowden Syndrome, because of the presence of multiple hamartomas in the oral mucose diagnosed a breast carcinoma, and other alterations such as thyroid calcifications and polyposis of the gastrointestinal tract.

PMID:
11589081
[PubMed - indexed for MEDLINE]
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