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    IEEE Trans Med Imaging. 2001 Sep;20(9):877-85.

    A constrained modulus reconstruction technique for breast cancer assessment.

    Samani A, Bishop J, Plewes DB.

    Department of Medical Biophysics, University of Toronto, ON, Canada. asamani@sten.sunnybrook.utoronto.ca

    A reconstruction technique for breast tissue elasticity modulus is described. This technique assumes that the geometry of normal and suspicious tissues is available from a contrast-enhanced magnetic resonance image. Furthermore, it is assumed that the modulus is constant throughout each tissue volume. The technique, which uses quasi-static strain data, is iterative where each iteration involves modulus updating followed by stress calculation. Breast mechanical stimulation is assumed to be done by two compressional rigid plates. As a result, stress is calculated using the finite element method based on the well-controlled boundary conditions of the compression plates. Using the calculated stress and the measured strain, modulus updating is done element-by-element based on Hooke's law. Breast tissue modulus reconstruction using simulated data and phantom modulus reconstruction using experimental data indicate that the technique is robust.

    PMID: 11585205 [PubMed - indexed for MEDLINE]

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