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Ear Nose Throat J. 2001 Sep;80(9):632-6, 638.

Localized laryngotracheobronchial amyloidosis: case report and review of the literature.

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  • 1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, P.O. Box 250582, 150 Ashley Ave., Charleston, SC 29425, USA.


Although localized laryngotracheobronchial amyloidosis is rare, the otolaryngologist--head and neck surgeon should be familiar with this condition. Its characteristic appearance can suggest its presence in a patient who has the typical initial symptoms. Biopsies during direct laryngoscopy and bronchoscopy can play both a diagnostic and therapeutic role. After an appropriate examination to rule out systemic involvement, the patient should be managed with conservative surgery, although the use of a CO2 laser might be more efficacious than conventional surgery. With appropriate diagnosis and treatment, patients should expect a favorable prognosis. In this article, we describe a new case of localized laryngotracheobronchial amyloidosis in a 67-year-old woman, and we review the literature on this subject.

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