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J Pept Res. 2001 Sep;58(3):229-36.

11-Demethylcyclosporins exhibit a single conformation in methanol and dimethylsulfoxide.

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  • 1Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic. sedmera@biomed.cas.cz

Abstract

NMR studies showed that 11-demethylcyclosporin A (cyclosporin E) and 11-demethylcyclosporin B exist as single species both in polar and nonpolar solvents. They adopt the same conformation that was found in the solid state.

PMID:
11576329
[PubMed - indexed for MEDLINE]
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