Cell. 2001 Sep 21;106(6):661-73.

Switching and signaling at the telomere.

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Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, USA. telomer@itsa.ucsf.edu

Abstract

This review describes the structure of telomeres, the protective DNA-protein complexes at eukaryotic chromosomal ends, and several molecular mechanisms involved in telomere functions. Also discussed are cellular responses to compromising the functions of telomeres and of telomerase, which synthesizes telomeric DNA.

PMID:: 11572773; [PubMed - indexed for MEDLINE]

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Cited by over 100 PubMed Central articles

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