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1: Curr Opin Investig Drugs. 2001 Apr;2(4):510-2.Links

IS-741 (Ishihara Sangyo).

Bassi C.

Surgical and Gastroenterological Department, University of Verona, Hospital GB Rossi, Verona, Italy. Claudio.Bassi@univr.it

IS-741 is a phospholipase A2 (PLA2) inhibitor under development by Ishihara Sangyo Kaisha and Sumitomo as a potential treatment for pancreatitis 1187575]. Sumitomo is developing the drug in phase II trials for acute pancreatitis 13990261. In an animal model, IS-741 has been shown to prevent pancreatitis-associated lung injury following endotoxemia [337503].

PMID: 11566008 [PubMed - indexed for MEDLINE]

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