Br J Cancer. 1975 Apr;31(4):429-33.

Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization.

Abstract

Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific enzyme oestrogen sulphotransferase.

PMID:: 1156524; [PubMed - indexed for MEDLINE]
PMCID:: PMC2009460

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