The effect of acute normovolaemic haemodilution on blood transfusion requirements in abdominal aortic aneurysm repair

Eur J Vasc Endovasc Surg. 2001 Oct;22(4):361-4. doi: 10.1053/ejvs.2001.1457.

Abstract

Objective: to evaluate the impact of acute normovolaemic haemodilution (ANH) on the blood transfusion requirements in elective abdominal aortic aneurysm (AAA) repair in a single vascular unit.

Methods: thirty-two patients underwent ANH during elective AAA repair between 1992 and 1997. The operation was performed by the same surgeon/anaesthetist team in 75% of cases. Their demographic details, type of aneurysm (infra-renal or supra-renal), preoperative blood cross match, use of intra-operative red cell salvage, blood loss, peri-operative bank blood requirements, pre-op and on-discharge haemoglobin levels and post-operative outcome were recorded. The results were compared to a group of 40 randomly selected patients (to represent the unit average) who underwent elective AAA repair by variable surgeon/anaesthetist teams without ANH in the same time period.

Results: there were more supra-renal AAA repairs in the ANH group (8/32) than in the non-ANH group (0/40, p<0.01). ANH patients required significantly less blood transfusion peri-operatively (median 2 units) than the non-ANH patients (median 3 units, p=0.02). There were no other significant differences between the variables measured.

Conclusion: these results suggest that a dedicated team can achieve significant reductions in the use of heterologous blood transfusion compared to the vascular unit average experience by the effective use of ANH.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm, Abdominal / surgery*
  • Blood Loss, Surgical
  • Blood Transfusion*
  • Blood Transfusion, Autologous
  • Blood Volume*
  • Female
  • Hemodilution*
  • Humans
  • Male
  • Middle Aged
  • Plasma Substitutes / administration & dosage
  • Retrospective Studies

Substances

  • Plasma Substitutes