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Phytother Res. 2001 Sep;15(6):549-51.

Kava and valerian in the treatment of stress-induced insomnia.

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  • Psychopharmacology Research Group, 10 Harley Street, London W1G 9PF, UK. wheatley@ukgateway.net

Abstract

Kava and valerian are herbal remedies, claimed to have anxiolytic and sedative properties respectively, without dependence potential or any appreciable side-effects. In this pilot study, 24 patients suffering from stress-induced insomnia were treated for 6 weeks with kava 120 mg daily. This was followed by 2 weeks off treatment and then, 5 having dropped out, 19 received valerian 600 mg daily for another 6 weeks. Stress was measured in three areas: social, personal and life-events; insomnia in three areas also: time to fall asleep, hours slept and waking mood. Total stress severity was significantly relieved by both compounds (p < 0.01) with no significant differences between them; as was also insomnia (p < 0.01). The proportion of patients with no side-effects was 58% with each drug respectively and the 'commonest' effect was vivid dreams with valerian (16%), followed by dizziness with kava (12% ). These compounds may be useful in the treatment of stress and insomnia but further studies are required to determine their relative roles for such indications.

Copyright 2001 John Wiley & Sons, Ltd.

PMID:
11536390
[PubMed - indexed for MEDLINE]
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