Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Genet Dev. 2001 Oct;11(5):554-60.

Notch signaling in lymphocyte development.

Author information

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, 471 Life Science Addition, Berkeley, California 94720, USA.


Signaling through Notch has been implicated in many cell-fate decisions during lymphocyte development. Recent studies have provided new clues--and raised new controversies--regarding the exact role that Notch signaling plays in the commitment of cells to the T-cell lineage. Progress has also been made in deducing the transcriptional program induced by Notch and the mechanism of oncogenic transformation by Notch in lymphocytes.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk