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Curr Opin Genet Dev. 2001 Oct;11(5):513-9.

Hematopoietic development: a balancing act.

Author information

  • 1Children's Hospital, Division of Hematology/Oncology, 300 Longwood Avenue, Boston, Massachusetts 02115, USA. alan.cantor@tch.harvard.edu

Abstract

Over the past year, significant new insights have been gained in our understanding of the lineage determination of red blood cells. In particular, evidence has emerged demonstrating that cross-antagonism of lineage-specific transcription factors plays an important role in determining cell phenotype by actively repressing alternate lineage gene programs.

PMID:
11532392
[PubMed - indexed for MEDLINE]
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