The genome of Mycobacterium leprae: a minimal myco...[Genome Biol. 2001]

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1: Genome Biol. 2001;2(8):REVIEWS1023. Epub 2001 Aug 3. Links

The genome of Mycobacterium leprae: a minimal mycobacterial gene set.

Vissa VD, Brennan PJ.

Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA. Varalakshmi.Vissa@colostate.edu

Comparison of the recently sequenced genome of the leprosy-causing pathogen Mycobacterium leprae with other mycobacterial genomes reveals a drastic gene reduction and decay in M. leprae affecting many metabolic areas, exemplified by the retention of a minimal set of genes required for cell-wall biosynthesis.

PMID: 11532219 [PubMed - indexed for MEDLINE]

PMCID: PMC138955

Deciphering the proteomic profile of Mycobacterium leprae cell envelope.
Proteomics. 2008 Jun; 8(12):2477-91.

[Proteomics. 2008]
ReviewGenomic evidence for the retention of the essential mycobacterial cell wall in the otherwise defective Mycobacterium leprae.
Lepr Rev. 2001 Dec; 72(4):415-28.

[Lepr Rev. 2001]
Biological implications of Mycobacterium leprae gene expression during infection.
J Mol Microbiol Biotechnol. 2004; 8(1):58-72.

[J Mol Microbiol Biotechnol. 2004]
ReviewThe decaying genome of Mycobacterium leprae.
Lepr Rev. 2001 Dec; 72(4):387-98.

[Lepr Rev. 2001]
Massive gene decay in the leprosy bacillus.
Nature. 2001 Feb 22; 409(6823):1007-11.

[Nature. 2001]
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