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    J Toxicol Clin Toxicol. 2001;39(4):409-11.

    Self-poisoning with Colchicum autumnale L. flowers.

    Danel VC, Wiart JF, Hardy GA, Vincent FH, Houdret NM.

    Département Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire, Grenoble, France. VDanel@chu-grenoble.fr

    A 44-year-old man ingested about 40 flowers of Colchicum autumnale L. The patient presented with nausea, vomiting, and abdominal pain 2 hours after ingestion and had diarrhea 14 hours after ingestion. Hematological values remained within normal range. Treatment was mainly supportive. The outcome was favorable. The intoxication was confirmed by high-performance liquid chromatography-mass spectrometry. Maximal colchicine levels were 4.34 ng/mL at 13 hours in plasma and 5.43 ng/mL at 16 hours in erythrocytes. CONCLUSION: We report one of the few symptomatic cases of Colchicum autumnale L. poisoning confirmed by toxicological analysis.

    PMID: 11527237 [PubMed - indexed for MEDLINE]

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