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J Basic Microbiol. 2001;41(3-4):185-227.

Fungal laccase: properties and activity on lignin.

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  • 1Department of Biochemistry, Maria-Curie-Sklodowska University, Pl-20031 Lublin, Poland.


The sources of ligninocellulose that occur in various forms in nature are so vast that they can only be compared to those of water. The results of several, more recent experiments showed that laccase probably possesses the big ability for "lignin-barrier" breakdown of ligninocellulose. The degradation of this compound is currently understood as an enzymatic process mediated by small molecules, therefore, this review will focus on the role of these mediators and radicals working in concert with enzymes. The fungi having a versatile machinery of enzymes are able to attack directly the "lignin-barrier" or can use a multienzyme system including "feed-back" type enzymes allowing for simultaneous transformation of lignin and carbohydrate compounds.

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