Format

Send to

Choose Destination
See comment in PubMed Commons below
J Chromatogr A. 2001 Jul 20;923(1-2):59-64.

Separation of proteins using hydrophobic interaction membrane chromatography.

Author information

  • 1Department of Engineering Science, University of Oxford, UK. raja.ghosh@eng.ox.ac.uk

Abstract

Membrane chromatography can overcome some of the problems associated with packed bed chromatography. In most membrane chromatographic studies reported so far, ion-exchange and affinity interactions have been utilised. In this paper the use of hydrophobic interactions for chromatographic separation is described. A polyvinylidene fluoride membrane was identified which could bind specific proteins in the presence of high ammonium sulphate concentration. The separation of CAMPATH-IG monoclonal antibody and bovine serum albumin using this membrane is discussed.

PMID:
11510560
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk