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Bull Acad Natl Med. 2001;185(4):777-84.

[Eradication of infectious diseases and vaccination].

[Article in French]

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  • 1Service de Pédiatrie Générale, Pathologie Infectieuse et Tropicale-Hôpital Armand Trousseau, 26 avenue du docteur Arnold Netter-75012 Paris.


Immunizations in man may act upon the infectious diseases development in three evolutive patterns: eradication, elimination, or disease control. Since the eradication of smallpox, very few diseases are at present candidates for a next eradication; poliomyelitis will be the first, perhaps followed by measles in many years. In spite of efficacious vaccines and a solely human reservoir, the eradication requires very strict conditions. However some diseases have been recently successfully eliminated: poliomyelitis (Americas, Europe, West Pacific regions), measles (i.e. Finland, United States), rubella (i.e. Finland). In spite of some limits, diphtheria, pertussis, hepatitis B are well controlled providing to get a sufficient vaccine coverage and to improve a sustained surveillance of those diseases. Regarding Haemophilus influenzae b, infections it is premature to predict a near elimination and the control is not yet well defined. National and regional programs have often to improve immunisation coverage and a better surveillance.

[PubMed - indexed for MEDLINE]
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