Psychopharmacology (Berl). 1979 Aug 8;64(2):131-4.

Reduction of MOPEG levels in cerebrospinal fluid of psychotic women after electroconvulsive treatment.

Härnryd C, Bjerkenstedt L, Grimm VE, Sedvall G.

Abstract

The effect of ECT on concentrations of monoamine metabolites in lumbar CSF of psychotic women with a schizophrenic symptomatology was examined. After a series of ECT there was a significant reduction of the concentration of the major noradrenaline metabolite, MOPEG. Levels of HVA, 5-HIAA, prolactin, or total protein in CSF were not significantly influenced by treatment. The results indicate a specific alteration of central noradrenaline metabolism in relation to ECT.

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