J Neurosci Res. 2001 Aug 1;65(3):191-4.
Neurofibromatosis type 1: II. Answers from animal models.
Lakkis MM, Tennekoon GI.
Department of Neurology, Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, Philadelphia, PA 19104-4399, USA. mlakkis@curagen.com
PMID: 11494353 [PubMed - indexed for MEDLINE]
Publication Types:
MeSH Terms:
- Animals
- Brain/abnormalities
- Brain/pathology
- Cell Transformation, Neoplastic/genetics
- Chimera
- Disease Models, Animal*
- Drosophila melanogaster/genetics
- Fibroblasts/pathology
- Ganglia, Sympathetic/abnormalities
- Ganglia, Sympathetic/pathology
- Gene Targeting
- Genes, Lethal
- Genes, Neurofibromatosis 1*
- Genes, p53
- Genotype
- Gliosis/genetics
- Gliosis/pathology
- Heart Defects, Congenital/genetics
- Heart Defects, Congenital/pathology
- Humans
- Insect Proteins/genetics
- Learning Disorders/genetics
- Loss of Heterozygosity
- Mice
- Mice, Knockout
- Mice, Mutant Strains
- Neoplastic Syndromes, Hereditary/genetics
- Nerve Tissue Proteins/deficiency
- Nerve Tissue Proteins/genetics
- Nerve Tissue Proteins/physiology
- Neural Crest/pathology
- Neurofibromatosis 1/genetics*
- Neurofibromatosis 1/pathology
- Neurofibromin 1
- Phenotype
- Rats
- Schwann Cells/pathology
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