J Asian Nat Prod Res. 2001;3(3):199-205.

The structure of physalin T from Physalis alkekengi var. franchetti.

Kawai M, Yamamoto T, Makino B, Yamamura H, Araki S, Butsugan Y, Saito K.

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Department of Applied Chemistry, Nagoya Institute of Technology, Japan. kawai@ach.nitech.ac.jp

Abstract

A new steroidal constituent named physalin T (3) was isolated from the aqueous extract of Physalis alkekengi var. francheti. Based on 1H and 13C NMR spectral studies the structure was assigned as 2,3-dihydrophysalin D, i.e., 5alpha,6beta-dihydroxy-2,3,5,6-tetrahydrophysalin B, which is the first example of a natural physalin possessing a saturated ring A moiety. The structure was confirmed by the chemical transformation from the known physalin D (2) to physalin T.

PMID:: 11491395; [PubMed - indexed for MEDLINE]

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The structure of physalin T from Physalis alkekengi var. franchetti.
The structure of physalin T from Physalis alkekengi var. franchetti.
J Asian Nat Prod Res. 2001 ;3(3):199-205.

PubMed
Steroids and flavonoids from Physalis alkekengi var. franchetii and their inhibi...
Steroids and flavonoids from Physalis alkekengi var. franchetii and their inhibitory effects on nitric oxide production.
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PubMed
Structures of physalin A and physalin B, 13,14-seco-16,24-cyclo-steroids from Ph...
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J Chem Soc Perkin 1. 1970 ;5:664-70.

PubMed
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The structure of physalin T from Physalis alkekengi var. franchetti.

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