Transcriptional regulation by the phosphorylation-dependent factor CREB.
Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
The transcription factor CREB -- for 'cyclic AMP response element-binding protein' -- functions in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in learning and memory. CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways?
PMID: 11483993 [PubMed - indexed for MEDLINE]