Nat Rev Genet. 2001 Aug;2(8):597-606.

The role of selfish genetic elements in eukaryotic evolution.

Source

Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK. g.hurst@ucl.ac.uk

Abstract

'Selfish genetic elements', such as transposons, homing endonucleases, meiotic drive chromosomes and heritable microorganisms, are common features of eukaryotes. However, their importance in the evolution of eukaryotic genomes is still controversial. In this review, we discuss these diverse elements and their potential importance in the evolution of genetic systems, adaptation, and the extinction and birth of species.

PMID:: 11483984; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

DNA Restriction Enzymes

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Review Shaping the genome--restriction-modification systems as mobile genetic elements. [Curr Opin Genet Dev. 1999]
Review Shaping the genome--restriction-modification systems as mobile genetic elements.
Kobayashi I, Nobusato A, Kobayashi-Takahashi N, Uchiyama I. Curr Opin Genet Dev. 1999 Dec; 9(6):649-56.
The evolutionary dynamics of repetitive DNA in eukaryotes. [Nature. 1994]
The evolutionary dynamics of repetitive DNA in eukaryotes.
Charlesworth B, Sniegowski P, Stephan W. Nature. 1994 Sep 15; 371(6494):215-20.
Review Selfish genetic elements, genetic conflict, and evolutionary innovation. [Proc Natl Acad Sci U S A. 2011]
Review Selfish genetic elements, genetic conflict, and evolutionary innovation.
Werren JH. Proc Natl Acad Sci U S A. 2011 Jun 28; 108 Suppl 2:10863-70. Epub 2011 Jun 20.
Review Finely orchestrated movements: evolution of the ribosomal RNA genes. [Genetics. 2007]
Review Finely orchestrated movements: evolution of the ribosomal RNA genes.
Eickbush TH, Eickbush DG. Genetics. 2007 Feb; 175(2):477-85.
Review Mobile elements and mammalian genome evolution. [Curr Opin Genet Dev. 2003]
Review Mobile elements and mammalian genome evolution.
Deininger PL, Moran JV, Batzer MA, Kazazian HH Jr. Curr Opin Genet Dev. 2003 Dec; 13(6):651-8.

See reviews... See all...

Cited by 41 PubMed Central articles

Genome differentiation in a species pair of coregonine fishes: an extremely rapid speciation driven by stress-activated retrotransposons mediating extensive ribosomal DNA multiplications. [BMC Evol Biol. 2013]
Genome differentiation in a species pair of coregonine fishes: an extremely rapid speciation driven by stress-activated retrotransposons mediating extensive ribosomal DNA multiplications.
Symonová R, Majtánová Z, Sember A, Staaks GB, Bohlen J, Freyhof J, Rábová M, Ráb P. BMC Evol Biol. 2013 Feb 14; 13:42. Epub 2013 Feb 14.
Selfish little circles: transmission bias and evolution of large deletion-bearing mitochondrial DNA in Caenorhabditis briggsae nematodes. [PLoS One. 2012]
Selfish little circles: transmission bias and evolution of large deletion-bearing mitochondrial DNA in Caenorhabditis briggsae nematodes.
Clark KA, Howe DK, Gafner K, Kusuma D, Ping S, Estes S, Denver DR. PLoS One. 2012; 7(7):e41433. Epub 2012 Jul 31.
Symbiotic associations in the phenotypically-diverse brown alga Saccharina japonica. [PLoS One. 2012]
Symbiotic associations in the phenotypically-diverse brown alga Saccharina japonica.
Balakirev ES, Krupnova TN, Ayala FJ. PLoS One. 2012; 7(6):e39587. Epub 2012 Jun 20.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Protein Clusters
Clusters of related proteins from the Protein Clusters database that cite the current articles. Sources of references in Protein Clusters include the associated Gene and Conserved Domain records as well as NCBI added citations.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Domains
Conserved Domain Database (CDD) records that cite the current articles. Citations are from the CDD source database records (PFAM, SMART).
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

The role of selfish genetic elements in eukaryotic evolution.
The role of selfish genetic elements in eukaryotic evolution.
Nat Rev Genet. 2001 Aug ;2(8):597-606.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: