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Org Lett. 2001 Aug 9;3(16):2539-41.

3-Aryl-2-oxazolidinones through the palladium-catalyzed N-arylation of 2-oxazolidinones.

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  • 1Dipartimento di Studi di Chimica e Tecnologia delle Sostanza Biologicamente Attive, Universit√† degli Studi La Sapienza, P.le A. Moro 5, 00185 Rome, Italy. sandro.cacchi@uniroma1.it

Abstract

[reaction: see text] 3-Aryl-2-oxazolidinones are obtained in good yields through the palladium-catalyzed N-arylation of 2-oxazolidinones with aryl bromides. The nature of aryl bromides, phosphine ligands, bases, and solvents strongly affects the reaction outcome.

PMID:
11483055
[PubMed - indexed for MEDLINE]
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