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Behav Res Ther. 2001 Aug;39(8):939-45.

Cognitive-behavior therapy for discontinuation of SSRI treatment of panic disorder: a case series.

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  • 1University of British Columbia Hospital, Anxiety Disorders Unit, UBC Hospital, Vancouver, Canada.


In this report we describe the outcome of eight outpatients with panic disorder and agoraphobia who discontinued their treatment with a selective serotonin reuptake inhibitor (SSRI) in the context of a structured, group program of cognitive-behavior therapy. All patients successfully discontinued their SSRI medication while demonstrating clinical improvement. These results were maintained at 3-month follow-up. This case series suggests that manualized CBT for discontinuation of benzodiazepine treatment for panic disorder may be successfully applied to SSRI discontinuation as well.

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