Transitional cell carcinoma of the urinary bladder following exposure to cyclophosphamide in childhood

S Agarwala; A K Hemal; A Seth; A K Gupta; V Bhatnagar; D K Mitra

doi:10.1055/s-2001-15486

Transitional cell carcinoma of the urinary bladder following exposure to cyclophosphamide in childhood

Eur J Pediatr Surg. 2001 Jun;11(3):207-10. doi: 10.1055/s-2001-15486.

Authors

S Agarwala¹, A K Hemal, A Seth, A K Gupta, V Bhatnagar, D K Mitra

Affiliation

¹ Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi. sandpagr@hotmail.com

PMID: 11475121
DOI: 10.1055/s-2001-15486

Abstract

With the increasing survival of children with malignancies, the long-term effects of chemotherapies are now becoming important and one of these dreadful long-term complications is the development of a second malignancy. Described here is a case of transitional cell carcinoma of the bladder developing 8 years following exposure to cyclophosphamide for the treatment of embryonal rhabdomyosarcoma.

Publication types

Case Reports

MeSH terms

Adolescent
Antineoplastic Combined Chemotherapy Protocols
Bone Neoplasms / congenital
Bone Neoplasms / drug therapy*
Carcinoma, Transitional Cell / chemically induced*
Carcinoma, Transitional Cell / diagnostic imaging
Carcinoma, Transitional Cell / therapy
Combined Modality Therapy
Cyclophosphamide / adverse effects*
Cyclophosphamide / therapeutic use
Cystoscopy / methods
Dactinomycin
Follow-Up Studies
Humans
Male
Monitoring, Physiologic
Radiography
Radiotherapy, Adjuvant
Rhabdomyosarcoma / congenital
Rhabdomyosarcoma / drug therapy*
Time Factors
Treatment Outcome
Urinary Bladder Neoplasms / chemically induced*
Urinary Bladder Neoplasms / diagnostic imaging
Urinary Bladder Neoplasms / therapy
Vincristine

Substances

Dactinomycin
Vincristine
Cyclophosphamide

Supplementary concepts

VAC protocol