Format

Send to:

Choose Destination
See comment in PubMed Commons below
Sex Transm Dis. 2001 Aug;28(8):472-6.

Association of Mycoplasma genitalium persistence in the urethra with recurrence of nongonococcal urethritis.

Author information

  • 1Department of Urology, Toyota Memorial Hospital, Toyota, Japan.

Abstract

BACKGROUND:

Most patients with recurrent symptomatic nongonococcal urethritis receive negative test results for Chlamydia trachomatis and Ureaplasma urealyticum, and the cause of such recurrence usually is unknown.

GOAL:

To assess the association of Mycoplasma genitalium with recurrent nongonococcal urethritis.

STUDY DESIGN:

In this study, 72 men with nongonococcal urethritis were treated with levofloxacin. Before and after treatment, symptoms and signs were assessed and first-pass urine was examined for C trachomatis, M genitalium, U urealyticum, and Mycoplasma hominis by polymerase chain reaction-based assays.

RESULTS:

In 6 of 45 men who had no symptoms and no evidence of inflammation after treatment, nongonococcal urethritis recurred. Of these 6 men, 5 had positive test results for M genitalium before levofloxacin treatment, which remained positive afterward. After the second treatment for recurrent nongonococcal urethritis, one man was still had a positive test result for the mycoplasma and experienced a subsequent recurrence.

CONCLUSIONS:

This study suggests that the persistence of M genitalium in the urethra may be associated with recurrence of nongonococcal urethritis.

PMID:
11473221
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Write to the Help Desk