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Pediatr Infect Dis J. 2001 Jul;20(7):716-8.

Short course directly observed therapy to monitor compliance with antiretroviral therapy in human immunodeficiency virus-infected children.

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  • 1Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY, USA.


We report our experience with short course directly observed therapy (DOT) in six human immunodeficiency virus-infected children who had a poor response to their prescribed therapy. Four to 8 days of DOT resulted in a significant drop in the viral load of all six children, demonstrating that short course DOT is an effective way to document poor compliance with antiretroviral therapy.

[PubMed - indexed for MEDLINE]
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