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Arch Dermatol. 2001 Jul;137(7):943-7.

Baldness and coronary artery disease: the dermatologic point of view of a controversial issue.

Author information

  • Department of Dermatology, Clinica Dermatologica, Viale Benedetto XV, 7, 16132 Genova, Italy. rebdermo@unige.it

Abstract

OBJECTIVE:

Several articles, most of them written by nondermatologists, have stressed that bald men have a higher risk for coronary artery disease than men who are not bald. This study was performed to evaluate the validity of such conclusions from a dermatologic point of view.

DESIGN:

A review of the 24 articles in literature from 1954 to 1999 as provided by MEDLINE and a previous review.

RESULTS:

Five articles contained simple comments; 1 was a review of the previous literature; and 3 dealt only with the lipid profile. The remaining 15 articles dealt with coronary artery disease and baldness, and 9 of these concluded that there is a relationship between the 2 conditions, especially in younger subjects with severe early-onset androgenetic alopecia.

CONCLUSIONS:

Baldness did not coincide with androgenetic alopecia in some of the articles examined, which makes it difficult to settle the issue. Subjects who develop baldness before their 30s may have a higher risk for coronary artery disease than other men, and they may be individuals with early-onset androgenetic alopecia who also present with particularly elevated dihydrotestosterone-testosterone ratios. The baldness theory should be included as a secondary hypothesis in large epidemiological studies of coronary artery disease. Such studies should include dermatologic expertise for accurate, cost-effective evaluation of baldness.

PMID:
11453815
[PubMed - indexed for MEDLINE]
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