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Curr Opin Genet Dev. 2001 Aug;11(4):464-9.

Cell movements during vertebrate development: integrated tissue behaviour versus individual cell migration.

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  • 1Instituto Cajal, CSIC, Avda Doctor Arce 37, 28002, Madrid, Spain.


Cell migration during development is fundamental to the establishment of the embryonic architecture. Depending on the context, cells may move either as integrated sheets of tissue or individually. Recently, molecules that are involved in both these types of cell behaviour have been identified, helping us to understand developmental processes as important as gastrulation and neural crest formation, and ultimately, the morphogenetic movements that shape the embryo.

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