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Nat Rev Genet. 2001 Jul;2(7):528-37.

Functional genomics and the study of development, variation and evolution.

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  • Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510, USA. kevin.white@yale.edu


It has rarely been possible to connect the developmental and evolutionary branches of genetics, particularly with regard to the precise changes in the molecular control of development that are responsible for phenotypic variation and evolution. Making such connections will require a high-resolution molecular description of the genetic networks that underlie development and an understanding of their responses to genetic and environmental variation. Functional genomics approaches to development and evolution promise to accelerate the research necessary to accomplish these goals.

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