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Diabetes Metab. 2001 Jun;27(3):383-5.

Erythropoietin-dependent anaemia: a possible complication of diabetic neuropathy.

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  • 1Department of Internal Medicine, Endocrinology and Diabetology, University Hospital, BP 577, 86021 Poitiers Cedex, France. cca.endocrino@chu-poitiers.fr

Abstract

We report the case of a 52-year-old woman with long-term type 1 diabetes mellitus, complicated with proliferative retinopathy, autonomic neuropathy and microalbuminuria and moderate renal failure. A normochromic, normocytic are generative anaemia had been diagnosed for three years. Clinical and biological investigations for the aetiology of anaemia remained normal or negative. Anaemia was associated with a concentration of erythropoietin (EPO) in the normal range, but inappropriately low regarding anaemia. Treatment with recombinant EPO induced a rapid increase in haemoglobin level and improved the patient's quality of life. The role of diabetic neuropathy in the genesis of anaemia, in conjunction with a modest renal impairment is discussed.

PMID:
11431605
[PubMed - indexed for MEDLINE]
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