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Nat Immunol. 2001 Jul;2(7):573-4.

ICOS costimulation: It's not just for TH2 cells anymore.

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  • 1Section of Pulmonary and Critical Care Medicine, Department of Medicine, and the Committee on Immunology, University of Chicago, Chicago, IL 60637, USA. asperlin@medicine.bsd.uchicago.edu

Abstract

A current paradigm has ICOS participating in TH2 costimulation. New data indicates ICOS regulates not only TH2 cells, but also TH1s.

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PMID:
11429535
[PubMed - indexed for MEDLINE]
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