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1: Genome Biol. 2001;2(6):REVIEWS1018. Epub 2001 Jun 5.Click here to read Click here to read Links

The origin and early evolution of mitochondria.

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada. M.W.Gray@dal.ca

Complete sequences of numerous mitochondrial, many prokaryotic, and several nuclear genomes are now available. These data confirm that the mitochondrial genome originated from a eubacterial (specifically alpha-proteobacterial) ancestor but raise questions about the evolutionary antecedents of the mitochondrial proteome.

PMID: 11423013 [PubMed - indexed for MEDLINE]

PMCID: PMC138944