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Genome Biol. 2001;2(6):REVIEWS0005. Epub 2001 Jun 5.

Evolution of mammalian genome organization inferred from comparative gene mapping.

Author information

  • 1Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702-1201, USA. murphywi@mail.ncifcrf.gov

Abstract

Comparative genome analyses, including chromosome painting in over 40 diverse mammalian species, ordered gene maps from several representatives of different mammalian and vertebrate orders, and large-scale sequencing of the human and mouse genomes are beginning to provide insight into the rates and patterns of chromosomal evolution on a whole-genome scale, as well as into the forces that have sculpted the genomes of extant mammalian species.

PMID:
11423011
[PubMed - indexed for MEDLINE]
PMCID:
PMC138942
Free PMC Article

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