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1: Genome Biol. 2001;2(6):REVIEWS0005. Epub 2001 Jun 5.Click here to read Click here to read Links

Evolution of mammalian genome organization inferred from comparative gene mapping.

Murphy WJ, Stanyon R, O'Brien SJ.

Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702-1201, USA. murphywi@mail.ncifcrf.gov

Comparative genome analyses, including chromosome painting in over 40 diverse mammalian species, ordered gene maps from several representatives of different mammalian and vertebrate orders, and large-scale sequencing of the human and mouse genomes are beginning to provide insight into the rates and patterns of chromosomal evolution on a whole-genome scale, as well as into the forces that have sculpted the genomes of extant mammalian species.

PMID: 11423011 [PubMed - indexed for MEDLINE]

PMCID: PMC138942